Brent Yarina, Senior Editor, February 20, 2016

The world's largest student-run philanthropy is back at it, as Penn State's annual "THON" kicked off late Friday afternoon at the Bryce Jordan Center.

[ MORE: Watch the 2016 THON live stream | Follow @THON on Twitter! ]

The event, which started in 1977 and raises benefits for pediatric cancer patients, features more than 700 students dancing for 46 consecutive hours, officially ending at 4 p.m. ET Sunday.

Throughout the 46-hour marathon, Penn State athletic teams will rotate in to take part in raising money for the Four Diamonds Fund out of Penn State Hershey Medical Center.

A year ago, THON raised $13,026,653.23, bringing the total to more than $125 million.